44 year-old male smoker, with history of melanoma of the scalp, who comes in with incidental (1.4x1.1cm) right middle lobe pulmonary nodule.
He underwent bronchoscopy with electromagnetic navigation bronchoscopy, FNA and TBBX of the RML nodule,
The smears and cell block demonstrate discohesive pleomorphic tumor cells. A panel of immunostains was performed. The tumor cells were positive for SOX-10, Mart 1, and S100 and negative for CK7, CK20, TTF-1, Napsin A, and p40.
FNA interpretation: Malignant cells present, consistent with melanoma.